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NEW RESEARCH SHOWS HOW TO BOOST GROWTH HORMONE

Kent Fischer - 13 Jan 2009


Most bodybuilders understand the important role growth hormone (GH) plays in building strength and muscle mass. GH stimulates an increase in muscle protein synthesis and  joint cartilage production, amino acid uptake by cells, and the use of fat for fuel. For optimum training results, natural production of GH must be at its peak.

Most bodybuilders don’t know this peptide hormone circulates in multiple molecular forms, only some of which are biologically active. Only a small fraction of GH produced actually exerts the biological effects that bodybuilders are after.


There is the intact immune-reactive form of GH (irGH). The immuno-functional GH (ifGH) represents the fraction of ir GH thatcontains these all-important binding domains; this is thefraction of GH that is biologically active.

In men, the bulk of bioactive GH (ifGH) secretion occurs at night. Studies show daytime production appears to be low. If we have a way to boost the level of bioactive GH during the day, it may provide faster muscle growth andmore effective fat loss.

Studies in the past have shown that both intense aerobic and resistance exercise stimulates GH secretion. The problem: scientists are not sure how much of the GH is the bioactive form.

A new study has shown how bodybuilders can increase their bioactive GH levels every time they train. For a really great guide to fast muscle building training click on No Nonsense Musclebuilding.

11 males participated in four experimental trials; two resting and two exercising. The bouts of exercise were short, fairly intense weight lifting workouts. Each trial was separated by one week. Just before each trial began, the men were given 3 grams of GABA or a placebo. Blood samples were taken and analyzed for ifGH up to 90 minutes after the dose.

GABA (Gamma Aminobutyric Acid), is an amino acid classified as a neurotransmitter. As a supplement, GABA has been shown in clinical trials to be remarkably consistent at elevating blood GH levels. In some cases by over 500%!. Though GABA is an effective GH-booster and, intense exercise spikes GH production during the day, no studies had examined the combined effect of taking GABA before an intense bout of exercise such as weight training.

Results:

At rest, a 3 gram dose of GABA elevated both GH and ifGH compared with a placebo. Specifically, peak concentrations of both hormones were elevated consistently, 375% above normal levels. That’s a consistent 375% in bioactive GH simply from taking GABA.

Weight training elevated both GH and its bioactive form significantly. The combination of GABA supplementation and weight training elevated both GH and ifGH concentrations around 175% greater than exercise alone.

So, exercise boosts the production of bioactive GH but taking GABA before exercise enhances this response, greatly.

GABA ingestion did not alter the ratio of bioactive ifGH to regular GH under all study conditions. Interestingly, ifGH represents approximately half (50%) of the irGH fraction.

The most important aspect of the study, was the level of control and quality of data. No one directly involved in the study knew who was getting what, and every participant was assessed under all 4 conditions; at rest (a does of GABA and placebo) and exercise (after a dose of GABA and the placebo). These procedures ensure that the data obtained is about as good as it gets.


WHAT THIS RESEARCH MEANS TO YOU

GABA can be used to boost the natural production of bioactive GH during the day when production is low.


Secondly,when training intensely you can be assured of a spike in bioactive GH. If you want to increase GH take a dose of GABA before each workout. The study shows you will experience a significantly greater increase in bioactive GH, than just exercising.

One final thing. In this study, subjects were given the supplement first thing in the morning, on an empty stomach. To ensure best GH response, bodybuilders should take their dose of GABA first thing in the morning, as soon as you open your eyes. When performing your morning workout, you can be assured of an optimum GH response from training.

For really fast muscle gains click on No 
Nonsense Musclebuilding.


1. Powers ME, Yarrow JF, McCoy SC, Borst SE, Growth hormone isoform responses to GABA ingestion at rest and after exercise. Med Sci Sports Exerc. 40, 104-10, 2008

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